Key Attributes of a Redox Drug

Title: Key Attributes of a Redox Drug:
Speaker: Kieron Wesson
Added: June 17, 2008
Category: Meet The Team

Transcript

A molecule that might function as a redox therapeutic has to have a number of features, we think. In terms of its redox capabilities, it has to be reversible, it has to be able to act catalytically. Be able to both receive electrons, and then give them away. And that means it can recycle itself, it can go through a redox event, recycle, and go back and do it again and again and again. We also think that therapy needs to have other properties - it needs to localize to the parts of the body, or the cell, where it can do that work. And, being a drug we hope we can do as much work as possible, with a small amount of the drug, and so, we really think it's important that a redox therapy is a reversible catalyst when it comes to redox. And that differs from an antioxidant, which generally, one would agree, is usually a one-way process. It sacrifices itself in its redox event and it's not available to recycle itself, and go through the motions again. So that's really the difference between an antioxidant and a redox therapeutic in my mind.