Starting with CoQ10

Title: Starting with CoQ10:
Speaker: Guy Miller
Added: June 17, 2008
Category: Chats with Guy

Transcript

Edison is beyond excited in our programs and it's not because we have great science, in fact we do, but it goes beyond that. There has been remarkable research done about the first chemical template that we're bringing forward, which is based on Coenzyme Q10 , which is central to the function of the mitochondria. There is a wealth of data suggesting that this molecular template has utility for diseases involving the mitochondria ranging from the classic respiratory chain diseases and on to diseases such as Huntington's, Parkinson's, and Alzheimer's. We here at Edison look at that as footprints in the sand. They are the inspirational remnants of fantastic observations which have been made by clinicians and basic scientists. Here at Edison we're focused three discrete questions around these wonderful observations. First, can we design a CoQ10 that overcomes the obstacle of being absorbed by the body? Secondly, can we improve the intrinsic activity of this compound by altering the redox nucleus? And third, can we build into the molecule certain features that will allow it to cross the blood brain barrier with alacrity. These three components, absorption, efficacy and blood brain barrier crossing, we think are our core competency with regard to Coenzyme Q10 and improving upon it and really building upon these wonderful footprints in the sand.